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### Clinical Trial Testing Feasibility of At-Home Immunotherapy for Non-Small Cell Lung Cancer

**LOS ANGELES ÔÇö A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.**

Immunotherapy, medicines that use the bodyÔÇÖs immune system to eliminate or control cancer cells, are effective for many cancer patients, but are currently only administered intravenously (into the vein) in a doctorÔÇÖs office or hospital.

The study will examine if a new formulation of atezolizumab, an immunotherapy approved for treating certain types of non-small cell lung cancer, can instead be safely and effectively administered subcutaneously, meaning it is injected under the patientÔÇÖs skin, by a nurse at the patientÔÇÖs home, along with telemedicine appointments and remote monitoring through wearable trackers.

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### Benefits of At-Home Cancer Treatment

Lung cancer is the second most diagnosed cancer in the world and the leading cause of cancer deaths for both men and women worldwide. Non-small cell lung cancer accounts for 81% of all lung cancer cases in the United States.

Immunotherapy is a relatively new treatment option approved to treat many cancer types both on its own or in combination with other therapies, such as radiation and chemotherapy.

Nieva believes that moving immunotherapy from a medical setting to the home will benefit patients. Patients will save time and energy traveling to a clinic or doctorÔÇÖs office, which can be especially difficult for those who are very sick, and they may feel more relaxed in their own homes. This could also potentially expand access to cancer treatment to patients who live in more remote areas or lack reliable access to transportation.

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### Clinical Trial Using Monoclonal Antibodies for Non-Small Cell Lung Cancer

The drug used in the clinical trial, atezolizumab, consists of a monoclonal antibody, a man-made protein that triggers the immune system to attack cancer cells. Investigators aim to enroll 37 patients with non-small cell lung cancer who are deemed eligible to receive immunotherapy as treatment. Patients will receive treatments administered by a nurse who will visit their home every three weeks for one to two years.

Additionally, Nieva and his colleagues will use the latest digital tools to track patientsÔÇÖ vital signs, physical activity, and other markers of health remotely and monitor patients with telehealth visits.

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By utilizing AI legalese decoder, potential participants can navigate the complexities of the clinical trial and make informed decisions about their involvement in the at-home cancer treatment study.

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