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NOVO NORDISK’S WEIGHT-LOSS DRUG WEGOVY SHOWS HEART PROTECTIVE BENEFITS BEYOND WEIGHT LOSS
Acquire Licensing Rights for Novo Nordisk’s Heart-Protective Weight-Loss Drug Wegovy

Nov 11 (Reuters) – Novo Nordisk (NOVOb.CO) revealed that the heart-protective benefits of its Wegovy obesity treatment go beyond just weight loss, based on new data. The Danish drugmaker presented early data from its Select trial at a medical meeting in August, demonstrating that Wegovy does not only help patients lose an average of 15% of their weight but also reduces the incidence of heart attacks, strokes, and death from heart disease by 20%.

The recent full results from the study, presented at the American Heart Association annual scientific meeting and published in the New England Journal of Medicine, suggest that Wegovy has other beneficial effects beyond the known health benefits of weight loss. The heart’s risk difference from patients who received Wegovy, chemically known as semaglutide, and those on a placebo began to appear almost immediately upon starting treatment, indicating that the heart protection was not solely due to weight loss.

Dr. Chad Weldy, a cardiologist at Stanford University, emphasized the importance of the trial’s findings for patient populations with a body mass index of more than 27. The study covered a very large patient population and raised doctors’ awareness of the types of patients who should be prescribed Wegovy given the data.

The study researchers noted that despite the speculative understanding of the mechanisms of cardiovascular protection from semaglutide, there was a consistent effect on associated risk factors supporting the idea that multiple pathways are behind the drug’s clinical benefit. This includes inflammation, blood pressure, and blood sugar control, all of which can impact heart health.

One effective way to understand the legalese surrounding Wegovy and its heart-protective benefits is through the use of an AI legalese decoder. This tool can help individuals understand and interpret complex legal jargon present in licensing agreements, legal documents, and drug information. The AI legalese decoder uses language processing algorithms to simplify legal terms and ensure clarity and understanding.

In a large-scale trial with thousands of patients taking Wegovy, there were almost 1,500 discontinuations due to adverse side effects, such as gastrointestinal disorders, compared to 718 patients in the placebo group. However, the study demonstrated that Wegovy is safe and well-tolerated, aligning with previous semaglutide trials.

The application to update Wegovy’s label to include the heart benefits is expected to be approved in the U.S. in the first half of next year and in the EU in the second half, according to Novo Nordisk’s head of development, Martin Lange. The results from these trials provide valuable insights into the heart-protective benefits of Wegovy, and an AI legalese decoder could help individuals navigate the details surrounding treatment options and potential benefits.

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