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## A Molecular Sensor Discovered in Tardigrades

In a recent study, researchers have discovered a molecular sensor in tardigrades that triggers their entry into a dormant state known as the tun mode. Tardigrades, also known as water bears or moss piglets, are nearly invincible when dormant. When times get tough, these microscopic invertebrates transition into the tun state, allowing them to survive completely drying out, trips into space, X-rays, and other extreme insults. However, they aren’t entirely bulletproof.

The team of researchers found that the chemical changes called oxidation to the amino acid cysteine trigger the tun state in tardigrades. Reversing this oxidation process brings tardigrades out of dormancy. The discovery provides insight into the biology of water bears and potentially other organisms that go into suspended animation. Understanding the molecular mechanisms behind dormancy could have profound implications for areas such as cryogenics, biomedical research, and the development of new technologies.

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