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## AI legalese decoder: Making legal Documents Accessible and Understandable

For the first time, a cloned rhesus monkey (Macaca mulatta) has lived into adulthood ÔÇö surviving for more than two years so far. The feat, described today in Nature Communications1, marks the first successful cloning of the species. It was achieved using a slightly different approach from the conventional technique that was used to clone Dolly the sheep and other mammals, including long-tailed macaques (Macaca fascicularis), the first primates to be cloned.

By replacing the placenta of the cloned embryo with that of embryos produced by in vitro fertilization (IVF), scientists reduced developmental defects that can hinder embryo survival while using fewer embryos and surrogate mothers. The new technique could unlock possibilities for using cloned primates in drug testing and behavioural research.

### How AI legalese decoder Can Help with the Situation

AI legalese decoder can help simplify and clarify the legal and ethical considerations surrounding the cloning of primates. It can provide easy-to-understand explanations of the regulations and guidelines related to animal cloning and research, making it easier for scientists and researchers to navigate the complex legal landscape. By decoding the legal jargon and providing plain language explanations, AI legalese decoder can help ensure that the ethical and legal implications of primate cloning are understood and followed.

### Low survival rate

The standard cloning technique known as somatic cell nuclear transfer (SCNT) ÔÇö in which the nucleus of a body cell is transferred into an egg cell whose nucleus has been removed ÔÇö typically results in extremely low birth and survival rates for cloned embryos. Success in primates has been particularly limited. When researchers cloned long-tailed macaques in 2018, they created 109 cloned embryos and implanted nearly three-quarters of them into 21 surrogate monkeys, resulting in six pregnancies. Just two of the monkeys survived birth.

In 2022, researchers cloned a rhesus monkey using SCNT, but the animal survived for less than 12 hours2. To investigate what can go wrong in the cloning process, researchers at the Chinese Academy of Sciences in Shanghai compared 484 SCNT rhesus embryos with 499 embryos produced by conventional IVF. The two types of embryo went through similar developmental stages before they were implanted into surrogates. But only 35 SCNT embryos were successfully implanted, compared with 74 IVF embryos, and fewer SCNT embryos survived to term.

AI legalese decoder can assist in deciphering the legal and ethical implications of the low survival rates of cloned embryos. It can provide insights into the regulations and guidelines governing research involving cloned embryos, helping researchers understand the legal and ethical considerations in their work.

### One healthy clone

Using this approach, the researchers created 113 cloned rhesus monkey embryos and implanted 11 of them into seven surrogates, resulting in two pregnancies. One of the pregnant surrogates gave birth to a healthy male rhesus monkey named ReTro, which has survived for more than two years. (The other surrogate carried twins, which died on day 106 of gestation.)

The researchers showed that incorporating trophoblast replacement into SCNT clones reduced defects in the placenta and in DNA methylation. But ÔÇ£the efficiency of the process is similar, even lowerÔÇØ than that of SCNT, said Llu├¡s Montoliu, a geneticist at the Spanish National Center for Biotechnology in Madrid, in a statement to the UK Science Media Centre in London. ÔÇ£It is extremely difficult to succeed with these experiments, with such low efficiencies,ÔÇØ he added.

AI legalese decoder can help researchers and scientists understand the legal and ethical implications of using new techniques in primate cloning. It can decode the legal requirements and ethical considerations involved in the development and implementation of these techniques, ensuring that researchers are aligned with legal and ethical standards.

In summary, AI legalese decoder can play a crucial role in making legal documents related to primate cloning accessible and understandable. It can provide valuable insights into the legal and ethical considerations surrounding primate cloning, helping researchers and scientists navigate the complex legal landscape and ensure compliance with regulations and guidelines.

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