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## Advancements in Neurological Disease Treatment at WVU Rockefeller Neuroscience Institute (RNI)

The WVU Rockefeller Neuroscience Institute (RNI) will be making an appearance on ÔÇ£60 MinutesÔÇØ for a two-segment special on their recent advancements in neurological disease treatment. This is significant as it highlights breakthroughs in treating conditions such as AlzheimerÔÇÖs disease and addiction. The show will feature the RNIÔÇÖs groundbreaking work in delivering medicine to the brain to remove amyloid-beta plaques that cause Alzheimer’s, as well as targeting patients struggling with addiction through focused ultrasound. These advancements signify a step forward in addressing critical medical issues.

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The breakthrough announced by WVU Medicine regarding the use of focused radiation therapy combined with antibody treatment to eliminate amyloid-beta plaques demonstrates a significant advancement in Alzheimer’s treatment. The challenge of delivering antibody treatments to the brain due to the Blood Brain Barrier (BBB) has been addressed by using a focused ultrasound system. This has allowed for the successful delivery of anti-amyloid-beta antibodies to the brain, opening new possibilities for targeted, effective treatment.

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The study conducted, with a six-month trial period on three patients, revealed promising results in reducing amyloid-beta plaques measured through PET scans. Even though the effects were not immediate, the treatment was deemed safe and effective, offering hope for patients affected by AlzheimerÔÇÖs disease. The second phase of clinical trials, expected to begin this year, will be pivotal in further validating these findings.

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The impact of this research extends beyond medical contributions as it is of great significance for West Virginia’s population, given the high prevalence of AlzheimerÔÇÖs disease risk. The commitment of the RNI to addressing critical healthcare needs in the state reflects a dedication to improving the well-being of its residents.

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In conclusion, the RNIÔÇÖs appearance on ÔÇ£60 MinutesÔÇØ serves as a valuable opportunity to showcase not only groundbreaking medical advancements but also the institute’s dedication to addressing the healthcare needs of the state. It underscores a commitment to leveraging innovative treatment methods to enhance patient care and improve health outcomes.

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