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## Impact of Winter Weather on COVID-19

### Updated Information on COVID-19 Variants

[Originally published: Dec. 10, 2023. Updated: Jan. 4, 2024]

Note: Information in this article was accurate at the time of original publication. Because information about COVID-19 changes rapidly, we encourage you to visit the websites of the Centers for Disease Control & Prevention (CDC), World Health Organization (WHO), and your state and local government for the latest information.

As cold winter weather drives people indoors and flu, colds, and other seasonal respiratory viruses circulate, SARS-CoV-2, the coronavirus that causes COVID-19, has continued to mutate and spread. Most recently a strain called JN.1 moved swiftly to become the most widely circulating variant in the United States, making up more than 60% of cases in early January.

While it can be difficult, if not impossible, to predict the evolution of the coronavirus and its descendants, the Centers for Disease Control and Prevention (CDC) projects that JN.1 cases will continue to rise through the winter. The World Health Organization (WHO) has declared it a ÔÇ£variant of interest.ÔÇØ There is no evidence that JN.1 causes more severe disease, the CDC says, but its rapid spread suggests it is either more transmissible or better at evading the immune system than other circulating variants.

Meanwhile, COVID activity in general has been rising, notes Heidi Zapata, MD, PhD, a Yale Medicine infectious diseases specialist. (That includes infections from variants such as HV.1, which in early January accounted for 14.8% of cases.) ÔÇ£I would say the most important thing for people to know is that the virus is out there, as are respiratory syncytial virus [RSV] and the flu. Any new subvariant is a sign that the SARS-CoV-2 virus is still evolving; itÔÇÖs still here with us, and we canÔÇÖt ignore it,ÔÇØ she says.

Here, Yale Medicine answers three questions about JN.1.

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