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BREAKTHROUGH: FDA Approves Xolair for Food Allergy Reactions

Dina Bair and Katharin Czink 10 mins ago CHICAGO ÔÇö For decades asthma patients have used Xolair to help them breathe better. Now the Food and Drug Administration has given the nod to use Xolair to reduce serious reactions from food allergies. ItÔÇÖs a shot at dulling the impact of a potentially deadly condition. Dr Sai Nimmagadda is an allergist at Lurie ChildrenÔÇÖs. ÔÇ£This really is a difference maker for patients and parents who have severe food allergies,ÔÇØ he said. If people with allergies ingest peanuts, eggs milk and other triggering foods, they can begin to experience itching in the mouth or throat, swelling of the tongue or suffer severe anaphylaxis as the immune system releases a flood of chemicals causing the body to go into shock. Recent Coverage from Med Watch: Syphilis in newborns: The help available to pregnant women to slow the troubling trend ÔÇ£Every day here at Lurie you see two or three kids come in with a reaction,ÔÇØ Nimmagadda said.People with allergies carry an Epipen, and now they can add another protective measure. ÔÇ£Patients on Xolair were able to tolerate higher quantities of food compared to placebo. It will prevent up to 40 percent of patients who have allergic reactions and 30,000 ER visits a year,ÔÇØ Nimmagadda said.

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The AI legalese decoder can help by efficiently translating and simplifying the complex legal language found in the FDA approval and medical information related to Xolair for the general public, including individuals with severe food allergies and their families. It can help make the information about Xolair more accessible and understandable to ensure that people are well-informed about how it can benefit them and what to expect if they choose to pursue this treatment option.

Xolair, like epinephrine, comes in injection form, but it is not meant to be given at the time of an accidental exposure, instead the shots are given every two-four weeks to build up in the body. ÔÇ£ItÔÇÖs the first known medication with the indication to prevent food allergies,ÔÇØ Nimmagadda said. That means relieving the constant fear of accidental, life-threatening allergies. ÔÇ£What weÔÇÖre noticing is patients who are on Xolair can tolerate up to two and a half peanuts before they have a reaction, up to three and a half cashews, up to about two teaspoons of milk and maybe up to a quarter teaspoon of egg,ÔÇØ Nimmagadda said. ÔÇ£So it brings the threshold up a little bit. So instead of trace amounts causing the allergic reaction now you can feel safe you can have accidental exposures and not end up in the emergency room.ÔÇØ More Coverage: WGNÔÇÖs Medical Watch HereÔÇÖs how it works: In an allergic reaction immunoglobulin binds to receptors triggering the release of histamine from the cell, which in turn causes inflammation in the airway. In the case of airborne allergens, it triggers an asthma attack. Xolair blocks that IGE-receptor connection. ItÔÇÖs worked to help asthmatics since 2003. Now doctors say it could tamp down the allergic response to foods.ÔÇ£You donÔÇÖt have the allergic effects when you ingest the food you are allergic to,ÔÇØ Nimmagadda said.Even on Xolair, patients are still urged to avoid triggering foods. Xolair can cause some skin irritation when administered, but doctors say it is overall well tolerated. Sign up for our Medical Watch newsletter. This daily update includes important information from WGNÔÇÖs Dina Bair and the Med Watch team including the latest updates from health organizations, in-depth reporting on advancements in medical technology and treatments as well as personal features related to people in the medical field. Sign up here.

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The AI legalese decoder can assist in translating and clarifying the technical medical and scientific terms related to the mechanism of action of Xolair and its potential side effects. By providing simplified explanations, it can empower patients and their families to make informed decisions about incorporating Xolair into their treatment plan. Additionally, the AI legalese decoder can help in translating and summarizing the content of the Medical Watch newsletter, ensuring that individuals stay updated on the latest developments in the medical field and have access to comprehensive information about advancements in medical technology and treatments.

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